Description:
TOFA is a cell-permeable, potent, reversible, and competitive allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). It inhibits the fatty acid biosynthesis by blocking the synthesis of malonyl-CoA.
- Molecular Weight:324.45
- Boiling Point:441.7±25.0 ℃ at 760 mmHg
- Melting Point:117-120 ℃
Molecular Formula:
C19H32O4
Canonical SMILES:
CCCCCCCCCCCCCCOC1=CC=C(O1)C(=O)O
InChI:
InChI=1S/C19H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22-18-15-14-17(23-18)19(20)21/h14-15H,2-13,16H2,1H3,(H,20,21)
InChIKey:
CZRCFAOMWRAFIC-UHFFFAOYSA-N
Solubility:
Soluble to ≥ 34 mg/mL in DMSO.
Application:
Hypolipidemic Agents
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
5-tetradecoxyfuran-2-carboxylic acid; 5-(tetradecyloxy)-2-furancarboxylic acid; 5-(tetradecyloxy)-2-furoic acid; RMI 14514; RMI-14514 Más detalles se encuentran
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